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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAN
All Species:
29.7
Human Site:
Y389
Identified Species:
46.67
UniProt:
Q9NQ55
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ55
NP_001035754.1
473
53194
Y389
Q
E
D
D
D
I
E
Y
F
C
Q
A
V
G
E
Chimpanzee
Pan troglodytes
XP_001150990
706
78742
Y389
Q
E
D
D
D
I
E
Y
F
C
Q
A
V
G
E
Rhesus Macaque
Macaca mulatta
XP_001100297
471
52923
Y389
Q
E
D
D
D
I
E
Y
F
C
Q
A
V
G
E
Dog
Lupus familis
XP_533920
792
88144
Y388
E
E
E
D
E
A
E
Y
F
R
Q
A
V
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91YU8
470
52707
Y388
D
E
E
D
D
A
E
Y
F
R
Q
A
V
G
E
Rat
Rattus norvegicus
NP_001011980
470
52521
Y388
E
E
E
D
D
A
E
Y
F
R
Q
A
V
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519003
490
55177
Y389
D
E
E
D
E
A
E
Y
F
R
Q
A
V
G
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_958871
522
59529
Y386
E
S
D
D
E
A
E
Y
Y
R
Q
A
V
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VDE5
460
53074
M379
P
D
E
E
L
F
K
M
E
A
K
S
S
R
K
Honey Bee
Apis mellifera
XP_395421
413
48031
E346
L
L
I
K
K
K
R
E
E
K
K
K
L
K
E
Nematode Worm
Caenorhab. elegans
NP_491108
573
63766
E410
E
E
V
E
N
Q
K
E
K
D
R
E
I
A
M
Sea Urchin
Strong. purpuratus
XP_787585
300
34175
S236
F
L
N
T
G
Q
L
S
E
S
E
A
E
L
D
Poplar Tree
Populus trichocarpa
XP_002302711
297
33281
S233
V
T
K
A
G
Y
G
S
E
S
E
G
D
D
E
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ASU7
345
38823
R281
K
L
Q
E
I
G
P
R
M
T
M
Q
L
V
K
Baker's Yeast
Sacchar. cerevisiae
P38789
453
51746
R376
K
R
H
A
A
K
M
R
L
K
E
Q
R
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.1
95.7
48.8
N.A.
73.3
73.5
N.A.
62
N.A.
N.A.
53
N.A.
35
38.9
31.4
36.3
Protein Similarity:
100
65.4
97.4
54
N.A.
81.6
81.8
N.A.
75.3
N.A.
N.A.
70.1
N.A.
57.5
59.2
49.5
47.9
P-Site Identity:
100
100
100
66.6
N.A.
73.3
73.3
N.A.
66.6
N.A.
N.A.
60
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
86.6
N.A.
80
N.A.
N.A.
80
N.A.
46.6
20
46.6
26.6
Percent
Protein Identity:
28.7
N.A.
N.A.
32.9
25.5
N.A.
Protein Similarity:
42.9
N.A.
N.A.
50.5
44.8
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
14
7
34
0
0
0
7
0
60
0
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
20
0
0
0
0
0
% C
% Asp:
14
7
27
54
34
0
0
0
0
7
0
0
7
7
7
% D
% Glu:
27
54
34
20
20
0
54
14
27
0
20
7
7
0
67
% E
% Phe:
7
0
0
0
0
7
0
0
47
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
14
7
7
0
0
0
0
7
0
54
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
7
0
7
20
0
0
0
0
0
0
7
0
0
% I
% Lys:
14
0
7
7
7
14
14
0
7
14
14
7
0
14
20
% K
% Leu:
7
20
0
0
7
0
7
0
7
0
0
0
14
7
0
% L
% Met:
0
0
0
0
0
0
7
7
7
0
7
0
0
0
7
% M
% Asn:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% P
% Gln:
20
0
7
0
0
14
0
0
0
0
54
14
0
0
0
% Q
% Arg:
0
7
0
0
0
0
7
14
0
34
7
0
7
7
0
% R
% Ser:
0
7
0
0
0
0
0
14
0
14
0
7
7
0
0
% S
% Thr:
0
7
0
7
0
0
0
0
0
7
0
0
0
0
0
% T
% Val:
7
0
7
0
0
0
0
0
0
0
0
0
54
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
54
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _